[Help] CI PHP error

I have an problem with my site it was runing well and this started to appear. Any help please ?

Code:

PHP Error was encountered

Severity: Warning

Message: require_once(/public_html/system/database/DB.php): failed to open stream: No such file or directory

Filename: core/Loader.php

Line Number: 337

Backtrace:

File: /public_html/application/core/MY_Controller.php
Line: 9
Function: __construct

File: /public_html/application/controllers/Admin.php
Line: 9
Function: __construct

File: /public_html/index.php
Line: 294
Function: require_once


Fatal error: require_once(): Failed opening required '/public_html/system/database/DB.php' (include_path='.:/opt/php-5.5/pear') in /public_html/system/core/Loader.php on line 337
A PHP Error was encountered

Severity: Compile Error

Message: require_once(): Failed opening required 'public_html/system/database/DB.php' (include_path='.:/opt/php-5.5/pear')

Filename: core/Loader.php

Line Number: 337

Backtrace:

require_once(/public_html/system/database/DB.php): failed to open stream: No such file or directory

Do you have /public_html/system/database/DB.php on your server?

ci-phpunit-test | CodeIgniter Testing Guide | CodeIgniter 3 to 4 Upgrade Helper

require_once(/public_html/system/database/DB.php): failed to open stream: No such file or directory

Do you have /public_html/system/database/DB.php on your server?

Yes I have it :|

If you can read /public_html/system/database/DB.php , why your web server (or PHP process) can't open it?
Someone has changed permission? or SELinux configuration?

ci-phpunit-test | CodeIgniter Testing Guide | CodeIgniter 3 to 4 Upgrade Helper

Like Kenjis said, there's only two possibilities : the path is wrong, or the permissions are wrong.

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