Cookies only setting in certain browsers

[eluser]pzntec[/eluser]
I think your globals and the function preg_replace confuses things. The preg_replace should be configured into the .htaccess file instead.

Have you tried the default settings?
<code>
$config['cookie_prefix'] = "";
$config['cookie_domain'] = "";
$config['cookie_path'] = "/";
$config['cookie_secure'] = FALSE;
</code>