[eluser]Aken[/eluser]
Sure it can. I'd prefer doing it with CodeIgniter's routes, though. Then all my URL modifications are in one place in case there's an issue.
Edit: Just saw you said redirects. You don't want to use a redirect in this situation, because it will actually force a page reload to the new URL. If you were to use .htaccess you'd want to set up a ModRewrite rule, not a redirect.