uri segment causing loading loop

I'm using Codeigniter 3.
I've removed the index.php with htaccess.
On some pages I'm using uri segments, but this is sometimes causing a loop of some part of the page.

Without the segments, the site is loaded correct.
But when adding segments to the same page, the page is first loaded correct, but after that some part of the site is loading many times.
In the source code, that part is only shown once.

I'v been searching for a solution, but I can't find any similar problem.
Can somebody help? Or has an idea what could be the problem.

Can you provide example code showing the problem? If the page is starting to download it sounds like it is not the segments causing the loop. What 'part of the site' is looping? Is it an ajax call?