Single application with multiple subdomains - how?

[eluser]frist44[/eluser]
You could do something like UPS where they ask you from the start your region and go into part of the app that caters to that content. Drop a cookie on their machine for that region, so it's remembered next time they come back.

You could also take a domain and rewrite the URL to a controller or something that would identify a region based on the subdomain and know to serve up the UK content.