Does the same error appear again when you hit the refresh button at the bottom of the "Paths" page?
Try adding ini_set('display_errors', 1); to the top of your CodeIgniter index.php. Also, enabling logging in your CodeIgniter config.php and check out the error log to see if anything is going there.
I suspect some kind of server error, but it is difficult to say what it might be without the error message.