routes working only in local

Codeigniter has nothing to do with the server it's being run on. The server, whether it's Apache, NGINX, LightHTTP, IIS or something else it needs to be set up to run the PHP application, whether it's CI or WordPress or something else. The application can't alter to webserver to "make itself run". No webserver runs PHP by default, except maybe PHP's built-in webserver.

Here's a working NGINX conf for a CI site:

Code:

server {
   listen 80;

   server_name YOUR_SERVER.com ;
   root /var/www/PATH_TO_SITE_ROOT;

   error_page 404 403 /404.html;

   location / {
       index index.html index.php; ## Allow a static html file to be shown first
       try_files $uri $uri/ @handler;
       expires 30d; ## Assume all files are cachable
   }

   ## These locations would be hidden by .htaccess normally
   location ^~ /application/        { deny all; }

   location  /. { ## Disable .htaccess and other hidden files
       return 404;
   }

   location @handler {
       rewrite / /index.php;
   }

   location ~ .php/ { ## Forward paths like /js/index.php/x.js to relevant handler
       rewrite ^(.*.php)/ $1 last;
   }

   location ~ .php$ { ## Execute PHP scripts
       if (!-e $request_filename) { rewrite / /index.php last; } ## Catch 404s that try_files miss

       expires        off; ## Do not cache dynamic content
       fastcgi_param  HTTPS $fastcgi_https;
       fastcgi_param  SCRIPT_FILENAME  $document_root$fastcgi_script_name;
       fastcgi_param  SITE_ENVIRONMENT development;
       fastcgi_pass   unix:/tmp/php-fpm.sock;
       include        fastcgi_params; ## See /etc/nginx/fastcgi_params
   }
}

The main things you would need to change with your values are:

Code:

server_name YOUR_SERVER.com ;
root /var/www/PATH_TO_SITE_ROOT;

and to set the site environment:

Code:

fastcgi_param  SITE_ENVIRONMENT development;

This configuration when I should I put it?

I have a vps with plesk with more sites installed.

Normally it should be inserted in /etc/nginx/nginx.conf, no?

I read that in the plesk 12 for nginx.config we can create a vhost_nginx.conf in /var/www/vhosts/system/domain/conf

But when I try to insert the file with your configuration
Nothing changes. I also tried to restart the nginx.
I always give me error 404.